Gene interactions and pathways from curated databases and text-mining

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BCRP6 — TP53

Text-mined interactions from Literome

Wang et al., FEBS Lett 2010 : Here, we investigate the effects of wild-type and mutant p53 , and nuclear factor kappa-B (NF-kappaB) ( p50 ) on BCRP promoter activity in MCF-7 cells ... Our results demonstrated that wild-type p53 markedly suppressed BCRP activity and enhanced the chemosensitivity of cells to mitoxantrone, whereas mutant p53 had little inhibitory effect
Wang et al., Int J Biochem Cell Biol 2013 : However, may be due to the physical interaction between p53 and Survivin, p53 directly affected Survivin regulated BCRP expressions