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BMP1 — TGFB1

Text-mined interactions from Literome

Ge et al., J Cell Biol 2006 : BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta binding protein ... TGFbeta1 is a potent inducer of ECM formation and of BMP1 expression
Lee et al., J Biol Chem 1997 (Osteosarcoma) : Here we show that BMP-1 is itself up-regulated by TGF-beta1 and that secreted BMP-1, induced by TGF-beta1, is either processed to an active form or remains as unprocessed proenzyme, in a cell type dependent manner ... Secreted BMP-1 and mTld, induced by TGF-beta1 in MG-63 and other fibrogenic cell cultures, were predominantly in forms in which proregions had been removed to yield activated enzyme ... In contrast to fibrogenic cells, keratinocytes lacked detectable PCPE under any culture conditions and were induced by TGF-beta1 to secrete BMP-1 and mTld predominantly as unprocessed proenzymes