Gene interactions and pathways from curated databases and text-mining

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BMP2 — FOXO1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: BMP2 → FOXO1 (increases, BMP2 Activity) Abid et al., J Biol Chem 2006*
    Evidence: The data revealed the existence of a novel set of VEGF-responsive genes that require FKHR activity for optimal expression in ECs, including bone morphogenic protein 2, cbp/p300-interacting transactivator 2, decay accelerating factor (DAF), vascular cell adhesion molecule-1 (VCAM-1), manganese superoxide dismutase, endothelial-specific molecule-1, RING1 and YY1 binding protein, and matrix metalloproteinase-10 and MGC5618