◀ Back to TNF

C9ORF3 — TNF

Text-mined interactions from Literome

Gueguen et al., Cell Biol Toxicol 2001 (Alzheimer Disease...) : Among several cytokines tested, only tumor necrosis factor (TNF)-alpha inhibited apo E secretion in basal conditions in CCF-STTG1 human astrocytoma cells ... In the presence of 25-hydroxycholesterol, TNF-alpha reduced apo E secretion by 80 %, while interleukins ( IL ) IL-1beta, IL-6, and IL-2 had no significant effects
Lopez et al., Br J Haematol 2003 : Apo-Tf or holo-Tf uniformly induced TNF-alpha secretion in the cell supernatants from both groups
Schulze-Osthoff et al., EMBO J 1994 : Whereas transcription factor NF-kappa B was readily activated by TNF , activation was not induced by triggering APO-1/Fas
Duan et al., J Clin Invest 1995 : Cytokines, including TNF alpha, have been identified in human lesions, therefore, we undertook a series of studies to evaluate the effect of TNF alpha on monocyte/macrophage apo E production ... In summary, TNF alpha stimulates apo E gene transcription, mRNA abundance, and protein synthesis in the monocyte/macrophage in a phenotype-specific manner
Lens et al., J Immunol 1996 (Burkitt Lymphoma) : In contrast to the strong effect of BCR ligation, APO-1 mAb induced apoptosis in only +/- 18 % of the Ramos cells after 48 h. Noticeably, addition of CD40 mAb or rTNF-alpha increased the percentage of cells ( +/- 46 % ) undergoing apoptosis, which correlated with an increase of Fas/APO-1 membrane expression induced by CD40 or TNF-R ligation