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CA2 — RAC3
Text-mined interactions from Literome
Arrieumerlou et al., J Immunol 2000
(Calcium Signaling) :
The major inhibitory
effect of
Rac mutants on
Ca2+ signaling is exerted on the activity of phospholipase C-gamma and, before that, on the phosphorylation of ZAP-70 and of the linker molecule for activation of T cells, LAT
Mehta et al., J Biol Chem 2005
:
We investigated the
role of intracellular
Ca2+ in signaling
Rac activation and the enhancement of endothelial barrier function ... Thus, our results demonstrate that S1P promotes endothelial junctional integrity by activating the release of endoplasmic
reticulum-Ca2+ , which
induces Rac activation and promotes AJ annealing
Grunicke et al., Crit Rev Eukaryot Gene Expr 2009
(Calcium Signaling) :
Likewise, Ras as well as
Rac control regulatory mechanisms,
resulting in increased or diminished levels of cytosolic-free
Ca2+ ... The biochemical mechanisms underlying these effects are discussed, with special reference to
regulation of
Ca2+ signaling by Ras and
Rac