Gene interactions and pathways from curated databases and text-mining

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CA8 — PTH

Text-mined interactions from Literome

Garg et al., Pflugers Arch 1976 : Failure of parathyroid hormone and cyclic AMP to inhibit renal carbonic anhydrase
Dawborn et al., Br J Pharmacol 1977 : The hypothesis that acetazolamide and parathyroid hormone (PTH) , inhibit renal carbonic anhydrase by a cyclic adenosine 3',5'-monophosphate ( cyclic AMP ) -dependent mechanism was also tested.2In vitro, acetazolamide, frusemide and ethacrynic acid at high concentrations ( 10 ( -3 ) M ) all produced some inhibition of basal and stimulated rat kidney plasma membrane adenylate cyclase
Hunter et al., J Bone Miner Res 1988 : The transient increase in acidity may be due to activation of carbonic anhydrase by PTH
Arlot-Bonnemains et al., Proc Natl Acad Sci U S A 1985 : The effect of calcitonin ( CT ) and parathyroid hormone (PTH) on carbonic anhydrase ( carbonate hydrolyase, EC 4.2.1.1. ) activity was tested in human erythrocyte hemolysates and with purified carbonic anhydrases I and II
Anderson et al., Calcif Tissue Int 1985 : Stimulation of carbonic anhydrase in osteoclasts by parathyroid hormone ... Because increased fluorescence of acridine orange is a sign of greater acidity, these results suggest that ( 1 ) PTH stimulates the acidity of osteoclasts, ( 2 ) carbonic anhydrase activity is necessary for maximum acidity, and ( 3 ) carbonic anhydrase is activated by PTH
DuBose et al., Artif Organs 1982 (Acid-Base Imbalance...) : PTH mediates bone buffering capacity by activating intracellular shifts of calcium, phosphorus, and carbonate or by stimulation of bone carbonic anhydrase
Nascimento et al., J Pharmacol Exp Ther 1977 : It has been recently demonstrated that parathyroid hormone (PTH) inhibits renal cortical carbonic anhydrase ... These data do not support the hypothesis that PTH inhibits bicarbonate and phosphate reabsorption by inhibiting carbonic anhydrase