Gene interactions and pathways from curated databases and text-mining

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CALM2 — CAPN15

Text-mined interactions from Literome

Brandt et al., J Membr Biol 1992 : The JFP has eight PEDST sequences ; this finding together with the calmodulin inhibition of calpain imply that the JFP is a PEDST-type calpain substrate ... These findings and the existence of PEDST sequences suggest that the JFP is normally degraded by calpain in vivo and that degradation is regulated by calpastatin and calmodulin
Hou et al., J Neurochem 2009 (Disease Models, Animal...) : Despite early increased expression of pCaMKII and pMAPK after just 10 min of glutamate treatment, only inhibitors to Ca ( 2+ ) /calmodulin dependent protein kinase II ( CaMKII ) and calpain prevented the occurrence of axonal varicosities
Greenwood et al., J Neurochem 1993 : Phosphorylation modulates calpain mediated proteolysis and calmodulin binding of the 200-kDa and 160-kDa neurofilament proteins
Croall et al., Biochim Biophys Acta 1996 : In order to demonstrate, unequivocally, that substrate recognition does not require an interaction between calpain and a substrate 's calmodulin binding domain, recombinant, full-length caldesmon and a mutant lacking the calmodulin binding domain were tested as substrates for calpain in the presence and absence of calmodulin