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CASP1 — GLI1

Text-mined interactions from Literome

Chen et al., World J Gastroenterol 2008 (Carcinoma, Hepatocellular...) : Gli-1 siRNA treatment also induced apoptosis by three criteria, increase in the sub-G1 cell cycle fraction, nuclear condensation, a morphologic change typical of apoptosis, and activation of caspase-3
Mazumdar et al., Cancer Res 2011 (Carcinoma...) : Pharmacologic inhibition of Gli1 and Gli2 by GANT61 or genetic inhibition by transient transfection of the Gli3 repressor (Gli3R) downregulated Gli1 and Gli2 expression and induced ?H2AX, PARP cleavage, caspase-3 activation, and cell death