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CAV3 — IL6

Text-mined interactions from Literome

Podar et al., J Biol Chem 2003 (Multiple Myeloma) : Interleukin-6 and insulin-like growth factor-I, growth and survival factors in multiple myeloma, induce caveolin-1 phosphorylation, which is abrogated by pre-treatment with beta-cyclodextrin
Wang et al., Am J Respir Cell Mol Biol 2006 (Inflammation) : Loss-of-function experiments using small interfering RNA showed that down regulating caveolin-1 expression in murine alveolar and peritoneal macrophages increased LPS induced proinflammatory cytokine TNF-alpha and IL-6 production but decreased anti-inflammatory cytokine IL-10 production
Wu et al., J Neurosurg 2010 (Brain Injuries...) : Simvastatin modified the caveolin-1 expression in lipid rafts in astrocyte cell membrane, suppressed the phosphorylation of EGFR in lipid rafts of astrocytes after OGD, and inhibited the OGD induced interleukin-1 production
Lv et al., Inflamm Res 2010 (Inflammation) : Over-expression of caveolin-1 not only increased the production of pro-inflammatory cytokine TNF-alpha and IL-6 , but also enhanced the expression of the cPLA2, p38 MAPK, and NF-kappaB
Hung et al., J Hypertens 2010 (Atherosclerosis) : Because eNOS and caveolin-1 are crucial for vascular tone control, we studied the effects of IL-6 on the expression and activation of eNOS and caveolin-1 in human vascular endothelial cells ... Furthermore, treatment with PD98059 and short interference RNA of extracellular signal regulated kinase gene reversed the effects of IL-6 on eNOS and caveolin-1
Wang et al., Am J Physiol Endocrinol Metab 2011 : Here, we address whether caveolin-1 is required for the first step of insulin 's transendothelial transport, its uptake by vascular endothelial cells ( ECs ), and whether IL-6 and TNFa affect insulin uptake or caveolin-1 expression ... IL-6 or TNFa also significantly reduced plasma membrane associated caveolin-1