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CCL11 — STAT6

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CCL11 → STAT6 (increases, CCL11 Activity) Fritz et al., J Immunol 2006*
  Evidence: IL-4 has been documented to regulate the expression of eotaxin-1 (41), eotaxin-2 (42), and eotaxin-3 (34) in endothelial cells and fibroblasts in a STAT6-dependent manner (42, 43, 44, 45). IL-4 signal transduction includes activation of STAT6 (46, 47, 48, 49, 50).

Text-mined interactions from Literome

Stevenson et al., J Leukoc Biol 2009 : We also discover that CCL11 inhibits GM-CSF mediated STAT5 activation and IL-4 induced STAT6 activation in a range of hematopoietic cells
Medoff et al., J Immunol 2009 (Disease Models, Animal...) : In this study, we demonstrate that STAT6 in bone marrow derived myeloid cells was sufficient for the production of CCL17, CCL22, CCL11 , and CCL24 and for Th2 lymphocyte and eosinophil recruitment into the allergic airway