Gene interactions and pathways from curated databases and text-mining

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CCL2 — CXCL2

Text-mined interactions from Literome

Gómez et al., J Immunol 2005 (Nasal Polyps) : Epithelial IL-6 and soluble IL-6Ralpha were shown to participate in trans signaling, interacting with membrane associated gp130 to activate CCL-2 expression and inhibit additional CXCL8 production
Hafez et al., Infect Immun 2009 : We show that the loss of capsule significantly reduced the level of monocyte chemoattractant protein 1 ( MCP-1 ), RANTES, macrophage inflammatory protein 2alpha ( MIP-2alpha ), MIP-2beta, interleukin-8, and gamma interferon-inducible protein 10 induction by Nissle 1917 in both Caco-2 cells and MCP-1 induction in ex vivo mouse small intestine
Li et al., J Clin Endocrinol Metab 2011 (Inflammation...) : In IL-1ß- or TNF-a stimulated first trimester decidual cells, NF?B inhibitor suppressed production of all six chemokines ; JUN NH2-terminal kinase inhibitor inhibited secretion of CCL2 , CCL4, and CCL5 ; and MAPK kinase and p38 inhibitor decreased production of CXCL8
Lai et al., Int J Gynecol Cancer 2011 (Genital Neoplasms, Female...) : Similar treatment in HeLa cells caused increases in the mRNA levels of CCL2 , CXCL2, IL-6, and IL-8, and in SKOV3 cells, mRNA levels of CCL2, CCL20, CXCL1, CXCL2 , IL-6, and IL-8 increased ... Similar treatment in HeLa cells caused increases in the mRNA levels of CCL2, CXCL2 , IL-6, and IL-8, and in SKOV3 cells, mRNA levels of CCL2 , CCL20, CXCL1, CXCL2, IL-6, and IL-8 increased