Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
CCND2
→
FOXO1
(directlyDecreases, CCND2 Activity)
Vogt et al., Cell cycle (Georgetown, Tex.) 2005* Evidence: They also repress transcription of cyclin D1 and D2, which results in an attenuation of CDK4 activity and reduced phosphorylation of Rb protein, and hence increased binding activity of E2F family members to Rb.