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CCND3 — CDK2

Pathways - manually collected, often from reviews:

• WikiPathways miRNA Regulation of DNA Damage Response: Complex of CDK4-CCND1-CDK6-CCND2-CCND3-CDK5 → Complex of CDK2-CCNE2-CCNE1 (inhibition)
  
• WikiPathways DNA Damage Response: Complex of CDK4-CCND1-CDK6-CCND2-CCND3-CDK5 → Complex of CDK2-CCNE2-CCNE1 (inhibition)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CCND3 — CDK2 (physical association, affinity chromatography technology) Datta et al., Cell Growth Differ 1998
• IRef Biogrid Interaction: CCND3 — CDK2 (physical association, affinity chromatography technology) Bockstaele et al., Mol Cell Biol 2006
• IRef Biogrid Interaction: CCND3 — CDK2 (physical association, affinity chromatography technology) Varjosalo et al., Nat Methods 2013

Text-mined interactions from Literome

Baldassarre et al., J Clin Invest 1999 (Thyroid Neoplasms) : In these cells, cyclin D3 induced the formation of cytoplasmic p27-cyclin D3-Cdk complexes, which titrated p27 away from intranuclear complexes that contain cyclins A-E and Cdk2
Hleb et al., J Biol Chem 2004 : The overall effect of rapamycin on cyclin D3 leads to impaired formation of active complexes with Cdk4 or Cdk6 and subsequent inhibition of cyclin D3/CDK kinase activity
Fu et al., Nutr Cancer 1997 (Melanoma, Experimental) : Serum limitation inhibited cyclin D1 and cyclin D3 expression to 24 % of control after four days and did not effect CDK expression