Gene interactions and pathways from curated databases and text-mining

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CD3G — CD69

Text-mined interactions from Literome

Testi et al., J Immunol 1989 : Activation of protein kinase C ( PKC ) by stimulation of the TCR/CD3 or by phorbol esters directly induces CD69 expression on T cells
D'Ambrosio et al., Eur J Immunol 1994 : The requirement for ras activation in T cell receptor (TcR) CD3 mediated CD69 induction was also investigated ... The expression of a dominant negative c-Ha-ras-N17 mutant markedly reduced the amount of GTP that could be immunoprecipitated from ras proteins after TcR/CD3 triggering in Jurkat cells, and concomitantly decreased TcR/CD3 mediated CD69 induction ... These results suggest a central role for ras in TcR/CD3 mediated CD69 expression in T cells