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CD3G — CD69
Text-mined interactions from Literome
Testi et al., J Immunol 1989
:
Activation of protein kinase C ( PKC ) by stimulation of the
TCR/CD3 or by phorbol esters directly
induces CD69 expression on T cells
D'Ambrosio et al., Eur J Immunol 1994
:
The requirement for ras activation in
T cell receptor (TcR) CD3 mediated
CD69 induction was also investigated ... The expression of a dominant negative c-Ha-ras-N17 mutant markedly reduced the amount of GTP that could be immunoprecipitated from ras proteins after TcR/CD3 triggering in Jurkat cells, and concomitantly decreased
TcR/CD3 mediated
CD69 induction ... These results suggest a central role for ras in
TcR/CD3 mediated
CD69 expression in T cells