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CD80 — TLR8

Text-mined interactions from Literome

Farina et al., Int Immunol 2004 : Both TLR-ligands and inflammatory cytokines induced the expression of CD25, CD69, CD80 and, surprisingly, also of CD83, commonly regarded as an activation marker for mature dendritic cells ( DC )
van Duin et al., J Infect Dis 2007 (Influenza, Human) : We determined TLR induced monocyte CD80/CD86 expression by flow cytometry and vaccine antibody responses by hemagglutination inhibition ... The mean increase in TLR induced CD80 ( + ) monocytes was reduced in older, compared with young, adults by 68 % ( P=.0002 ), and each decile increase of CD80 ( + ) cells was associated with an 8.5 % increase in mean number of vaccine strains with a > or =4-fold titer increase ( P=.01 ) and a 3.8 % increase in mean number of strains with a postvaccine titer > or =1 : 64 ( P=.037 )
Funderburg et al., Proc Natl Acad Sci U S A 2007 : Here, we show that human beta-defensin-3 (hBD-3), an innate antimicrobial peptide, can induce expression of the costimulatory molecules CD80 , CD86, and CD40, on monocytes and myeloid dendritic cells in a TLR dependent manner
Trujillo et al., J Investig Allergol Clin Immunol 2011 (Common Variable Immunodeficiency) : Interestingly, CD80 and CD86 expression on innate cells upon stimulation with TLR ligands was not altered in the patients although 3 of them exhibited low baseline levels of these surface molecules on monocytes compared to healthy controls
Shimada et al., Nephrol Dial Transplant 2012 : We therefore evaluated the ability of TLR to induce CD80 in human cultured podocytes