Gene interactions and pathways from curated databases and text-mining

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CDH12 — CDH2

Text-mined interactions from Literome

Wei et al., J Biol Chem 2005 : Studies using siRNA knockdown indicated that cell surface expression of Cx43alpha1 required N-cadherin , and conversely, N-cadherin cell surface expression required Cx43alpha1
Derycke et al., Clin Exp Metastasis 2006 : In vitro experiments with PD173074 and knock-down of N-cadherin and fibroblast growth factor ( FGF ) -receptor, showed that the pro-angiogenic effect of soluble N-cadherin is N-cadherin- and FGF-receptor dependent
Haÿ et al., Mol Cell Biol 2009 : N-cadherin overexpression in osteoblasts increases N-cadherin-LRP5 interaction, causing increased beta-catenin degradation and altered TCF/LEF transcription in response to Wnt3a
Yuan et al., Int J Oncol 2009 : The treatment of 3Y1 cells that express E7 ( E7-3Y1 ) with MEK inhibitor recovered the cadherin mediated cell adhesion together with the accumulation of N-cadherin at the cell-cell contact site
Reneker et al., Brain Res Bull 2010 : The E/EnMT in the transgenic mouse cornea was further demonstrated by loss of E- and N-cadherin expression in the corneal epithelial and endothelial cells, respectively, and meanwhile increasing expression of cadherin-11 in both corneal epithelium and stroma