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Tsuda et al., Oncogene 2005
(Sarcoma, Synovial) :
Here, we present a novel finding that human chimeric oncoprotein SYT-SSX1 induces CKI p21 ( WAF1/CIP1 ) ( p21 ) for suppression of cell growth ... The transient expression of SYT-SSX1 induced activation of the p21 gene promoter in human diploid fibroblasts
Kim et al., Exp Mol Med 2009
:
In addition, SHP induced the cell cycle regulatory protein levels and cooperatively increased an induction of p21WAF1 expression with p65 Ji et al., Anticancer Drugs 2009
(Lung Neoplasms) :
Consistent with our earlier observation that p21 is induced in an NFkappaB/p65 dependent manner, we conclude that p21 plays an important role in mediating cell growth inhibition by gefitinib
Zhou et al., J Biomed Sci 2012
:
Cytoplasmic p21 induced by p65 prevents doxorubicin induced cell death in pancreatic carcinoma cell line