UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CEBPB — FOS

Pathways - manually collected, often from reviews:

NCI Pathway Database IL6-mediated signaling events: CEBPB (CEBPB) → AP1 complex (FOS-JUN) (transcription, activates) Schumann et al., Mol Cell Biol 1996 *
Evidence: mutant phenotype, reporter gene, physical interaction

Text-mined interactions from Literome

Cho et al., Mol Pharmacol 2003 : AP-1 decoy oligonucleotide suppressed C2-potentiated C/EBP beta expression, indicating that AP-1 was responsible for C2-mediated C/EBP beta expression
Gagliardi et al., J Biol Chem 2003 : In contrast, the over-expression of C/EBPbeta caused a dramatic reduction in the levels of AP-1 proteins