Gene interactions and pathways from curated databases and text-mining

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CEP290 — PTGS2

Text-mined interactions from Literome

Mizumura et al., Clin Exp Allergy 2003 (Influenza, Human...) : The results showed that ( 1 ) IV infection increases COX-2 expression, cPLA2 phosphorylation and PGE2 release, ( 2 ) ERK, p38 MAPK and JNK were phosphorylated, ( 3 ) CEP-11004 and PD 98059 predominantly attenuated COX-2 expression and cPLA2 phosphorylation, respectively, ( 4 ) SB 203580 did not remarkably affect COX-2 expression and cPLA2 phosphorylation, and ( 5 ) each inhibitor dose-dependently attenuated PGE2 release by various extents
Fang et al., Int J Gynecol Cancer 2013 : The inhibitory effects of CEP on STAT3 signaling pathway and COX-2 help us to better understand the radiosensitization of CEP