Gene interactions and pathways from curated databases and text-mining

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CASP3 — CPOX

Text-mined interactions from Literome

Sánchez-Alcázar et al., Lung Cancer 2003 (Carcinoma, Non-Small-Cell Lung...) : These observations suggest that COX inhibitors induce apoptosis in non-small lung cancer cells through cytochrome c and AIF release, and subsequent caspase activation, independently of COX-2 expression and prostaglandin production
Laschke et al., Fertil Steril 2007 : Moreover, COX-2 inhibition suppressed cell proliferation and induced apoptosis associated caspase-3 expression