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CREM — PRKACB
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Cho et al., Yonsei Med J 2005
:
The induction of
ICER mRNA expression by rolipram was
suppressed by the inhibitors of
protein kinase A (PKA) and p38 MAPK, suggesting the involvement of PKA and p38 MAPK activation in ICER expression by rolipram
Ding et al., Proc Natl Acad Sci U S A 2005
:
PDE3A down-regulation activated cAMP/PKA signaling, leading to ICER up-regulation via
PKA dependent stabilization of
ICER
Abderrahmani et al., EMBO J 2006
(Hyperglycemia) :
We demonstrate that the transcriptional repressor
ICER , which is induced in a
PKA dependent manner by chronic hyperglycemia and cAMP raising agents, is responsible for the decline of the four genes
Ohtsubo et al., Arterioscler Thromb Vasc Biol 2007
(Disease Models, Animal) :
The induction of ICER was inhibited by pretreatment with H89, a protein kinase A (PKA) inhibitor, suggesting that
PKA mediates the induction of
ICER expression