Drayer et al., Stem Cells 2005
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SCF induced enhancement of JAK2 phosphorylation was not affected by inhibition of Src kinase, suggesting that both JAK2 and Src kinase mediate STAT5 tyrosine phosphorylation
Tang et al., Mol Cell Biol 1994
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Conversely, the cytoplasmic kinase JAK2 is activated by IL-3 but not by SCF stimulation
Weiler et al., Blood 1996
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These data demonstrate that SCF induces tyrosine phosphorylation of JAK2 and suggest that JAK2 is a component of the SCF signal transduction pathway
Deberry et al., Biochem J 1997
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We recently found that the Janus kinase Jak2 associates with c-kit and that SCF induces rapid and transient phosphorylation of Jak2