Gene interactions and pathways from curated databases and text-mining

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CXCL12 — PDGFB

Text-mined interactions from Literome

Song et al., Cancer Res 2009 (Breast Neoplasms...) : In the current study, we show that tumor derived PDGF-BB induces SDF-1alpha expression in endothelial cells ( EC ), resulting in the formation of SDF-1alpha chemotaxis gradient, which coincides with the PDGF-BB induced pericyte recruitment during angiogenesis
Hamdan et al., Mol Cancer Res 2011 : SDF-1a induces PDGF-B expression and the differentiation of bone marrow cells into pericytes ... The purpose of this study was to investigate the mechanism by which SDF-1a increased PDGF-B expression and the role of this pathway in BM-derived pericyte differentiation ... These findings show that SDF-1a regulates PDGF-B expression and that this regulation plays a critical role in the differentiation of PDGFR-ß+ BMCs into mature pericytes