Gene interactions and pathways from curated databases and text-mining

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ARPC4 — CYFIP1

Text-mined interactions from Literome

Suetsugu et al., J Cell Biol 2006 : WAVE2 activates the actin related protein (Arp) 2/3 complex for Rac induced actin polymerization during lamellipodium formation and exists as a large WAVE2 protein complex with Sra1/PIR121, Nap1, Abi1, and HSPC300
Nakanishi et al., J Biochem 2007 : Effect of WAVE2 phosphorylation on activation of the Arp2/3 complex
Shakir et al., Genetics 2008 : Experiments are described here that indicate that, in Caenorhabditis elegans, two WH2-domain containing activators of the Arp2/3 complex , WVE-1/WAVE and WSP-1/WASP, act redundantly in axon guidance and that GEX-2/Sra-1 and GEX-3/Kette, molecules that control WAVE activity, might act in both pathways