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Wang et al., American journal of physiology. Renal physiology 2000
(Diabetes Mellitus, Experimental...) :
In the present studies, the hypothesis is examined that ultrafiltered HGF and TGF-beta induce increased expression of extracellular matrix ( ECM ) proteins directly in tubular cells, or induce increased expression of cytokines that may act on interstitial myofibroblasts
Liu et al., Kidney Int 2000
(Chronic Disease...) :
The effects of HGF on extracellular matrix ( ECM ) synthesis and degradation were examined in renal epithelial cells by ( 35 ) S-methionine labeling, Western blotting, and zymographic analysis ... In vitro studies revealed that HGF reduced net ECM accumulation by human proximal tubule cells ( HKC ), and this effect was abolished by incubating cells with an anti-HGF antibody