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CCND1 — EDN1

Text-mined interactions from Literome

Mishra et al., Mol Pharmacol 2005 : To further explore the role of Src in mitogenic signaling by G protein coupled receptors, we sought to determine whether endothelin-1 induced cyclin D1 by a Src based mechanism ... We found that endothelin-1 increased cyclin D1 protein, which was blocked by preincubation with the Src antagonist PP2 and with the protein kinase C antagonist bisindolylmaleimide I ... These results provide evidence for a Src- and protein kinase C-based pathway of mitogenic signaling by endothelin-1 receptors that involves cyclin D1
Murata et al., Cancer Sci 2007 (Melanoma...) : Although the stimulation with endothelin-1 plus calcium chloride increased cyclin D1 protein levels after 4-6 h, the level of phosphorylated retinoblastoma protein did not increase, suggesting that overexpression of cyclin D1 protein may have little effect on cell cycle progression but rather act as a pro-survival factor
Michinaga et al., Neurochem Int 2013 : Endothelin-1 stimulates cyclin D1 expression in rat cultured astrocytes via activation of Sp1