Gene interactions and pathways from curated databases and text-mining

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EGFR — MCL1

Text-mined interactions from Literome

Yoon et al., Cancer Res 2002 (Cholangiocarcinoma...) : The deoxycholate mediated increase of cellular Mcl-1 protein was blocked equally by EGFR tyrosine kinase inhibitors or an EGFR neutralizing antibody
Chan et al., J Immunol 2010 : PI3K dependent upregulation of Mcl-1 by human cytomegalovirus is mediated by epidermal growth factor receptor and inhibits apoptosis in short lived monocytes ... Lastly, we showed that HCMV engagement and activation of the epidermal growth factor receptor during viral binding triggered the upregulation of Mcl-1
Fassl et al., Oncogene 2012 (Glioblastoma) : Notch1 signaling promotes survival of glioblastoma cells via EGFR mediated induction of anti-apoptotic Mcl-1 ... Notch1 dependent regulation of Mcl-1 occurs cell type dependent at a transcriptional or post-translational level and is mediated by the induction of epidermal growth factor receptor (EGFR)