Spicer et al., Oncogene 2003
(Colorectal Neoplasms...) :
Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1 ... Here we show that LKB1 can direct the phosphorylation of the serine-threonine kinase PAR1A Wang et al., J Neurosci 2007
(Tauopathies) :
Diverse stress stimuli, such as high osmolarity and overexpression of the human beta-amyloid precursor protein, can promote PAR-1 activation and tau phosphorylation in an LKB1 dependent manner
Hurov et al., Cell cycle (Georgetown, Tex.) 2007
:
Par-1 is regulated by LKB1 and atypical PKC and has been shown in multiple organisms and cell types to be critical for regulation of cellular polarity