Gene interactions and pathways from curated databases and text-mining

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CA2 — FASLG

Text-mined interactions from Literome

Contini et al., J Immunol 2005 : Moreover, FasL up-regulation and CTL apoptotic death were down-regulated by pharmacological specific inhibitors of Ca2+/calmodulin/calcineurin and Ca2+ independent protein kinase C signaling pathways
Esser et al., J Exp Med 1998 : These results further define the role of Ca2+ in perforin and FasL/Fas killing and demonstrate that differential Ca2+ signaling can modulate T cell effector functions