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FASLG — IRF6

Text-mined interactions from Literome

Yamamoto et al., Drug design and discovery 1999 : We studied the inhibitory effects of various hydroxamate MMP inhibitors on FasL and TNF-alpha processing in order to characterize the processing enzymes using human FasL cDNA transfectants and LPS stimulated THP-1 cells
Lau et al., J Surg Res 2001 (Glioma...) : Both Kupffer cells and LPS/Kupffer cell conditioned supernatants induced expression of Fas and Fas ligand on malignant glioma cells
Faggioni et al., J Immunol 2001 (Granuloma...) : Given 10 min before LPS challenge to mice primed 12 days in advance with heat killed Propionibacterium acnes, IL-18BP-Fc prevents LPS induced liver damage and IFN-gamma and Fas ligand expression
Fukui et al., J Immunol 2003 : LPS stimulation induced the expression of Fas, caspase 8, cellular FLIP Bfl-1/A1, and Bcl-x, but not FasL , TNFR p55, Bak, Bax, and Bad at the transcriptional level
Hiromatsu et al., Eur J Immunol 2003 (Escherichia coli Infections) : In a manner analogous to E. coli infection, lipoprotein and LPS could additively induce Fas L expression on NK1.1 ( + ) T cells, leading to liver injury in vivo in normal mice but not in gld/gld mice
Uchikura et al., Am J Physiol Gastrointest Liver Physiol 2004 : LPS stimulation of KC resulted in upstream ROS generation and, subsequently, increased FasL expression and consequent Jurkat cell ( Fas positive ) apoptosis
Shimizu et al., Hepatology research : the official journal of the Japan Society of Hepatology 2005 : LPS also enhanced equally the mRNA expression of Fas but not Fas ligand irrespective of either genotype, as measured by RNase protection assay
Dimayuga et al., J Neuroimmunol 2005 (Encephalitis) : Specifically, the effects of 17beta-estradiol on basal and LPS induced surface staining of Class I and II MHC, as well as CD40, CD80, CD86, CD152, CD28, CD8, CD11b, Fas, FasL , and also ERalpha and ERbeta, were examined in N9 microglial cells
Peng et al., Cytokine 2007 : RKC1 and RKC2 are similar to primary Kupffer cells as they express the molecular markers ED1, ED2, ED3, and F4/80, and upregulate TNF-alpha, IL-6, IL-1beta, Fas /FasL , and NF-kappaB, as well as TLR4 in response to LPS or pancreatic elastase
Peng et al., J Gastrointest Surg 2007 (Sepsis...) : AdPKC-zeta DN attenuated the LPS induced upregulation of PKC-zeta activity, IKKbeta, IKKgamma, NF-kappaB, Fas/FasL , Caspase-3, and DNA fragmentation in Kupffer cells ( all p < 0.001 ), whereas overexpression of PKC-zeta augmented LPS induced upregulation of IKKbeta, IKKgamma, NF-kappaB, Caspase-3, and DNA fragmentation ( p < 0.001 )
Ortiz-Arduan et al., Am J Physiol 1996 (Endotoxemia) : These data suggest that transcripts encoding natural FasL and Fas are induced by LPS and may play a role in endotoxemia induced acute renal failure and organ dysfunction
Halaas et al., J Immunol 1998 : The LPS- or mannuronan induced cytotoxicity was due to increased Fas ligand (FasL) expression by BMC, since 1 ) Fas transfected L1210-Fas target cells were more susceptible to lysis than the Fas ( low ) -expressing parent L1210 cells, 2 ) stimulated BMC from FasL-defective gld/gld mice were not cytolytic and, 3 ) the cytolytic activity of normal BMC was inhibited by a Fas-Fc fusion protein