Gene interactions and pathways from curated databases and text-mining

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FGF2 — NOX3

Text-mined interactions from Literome

Tsukamoto et al., J Neurosci Res 2003 (Alzheimer Disease) : Further investigation suggested that Abeta neurotoxicity via p75NTR involved JNK, NADPH oxidase , and caspases-9/3 and was inhibited by activity dependent neurotrophic factor, insulin-like growth factor-I, basic fibroblast growth factor , and Humanin, as observed in primary neuron cultures
Schröder et al., Arterioscler Thromb Vasc Biol 2007 : These data demonstrate that bFGF activates the Nox1 containing NADPH oxidase and that bFGF through a pathway involving ROS and JNK stimulates SMC migration
Black et al., Am J Physiol Cell Physiol 2008 : In addition, FGF-2 mediated increases in FGF-2 expression and PASMC proliferation were attenuated by inhibition of phosphatidylinositol 3-kinase, Akt, and NADPH oxidase