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FGF4 — RUNX2

Text-mined interactions from Literome

Kim et al., J Biol Chem 2003 : The protein kinase C pathway plays a central role in the fibroblast growth factor stimulated expression and transactivation activity of Runx2 ... Fibroblast growth factor ( FGF ) /FGF receptor ( FGFR ) signaling induces the expression of Runx2 , a key transcription factor in osteoblast differentiation, but little is known about the molecular signaling mechanisms that mediate this ... Thus, we show for the first time that FGF/FGFR signaling stimulates the DNA binding and transcriptional activities of Runx2 as well as its expression, and these are largely regulated by the PKC pathway
Aberg et al., Dev Biol 2004 : Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis
Park et al., J Biol Chem 2010 : However, the molecular mechanism underlying Runx2 activation by FGF/FGFR or ERK was still unclear
Lu et al., Dev Dyn 2012 : Molecular studies on the roles of Runx2 and Twist1 in regulating FGF signaling ... In this study, we assessed the roles of Runx2 and its functional antagonist Twist1 in regulating fibroblast growth factor ( FGF ) signaling using in vitro biochemical approaches