Gene interactions and pathways from curated databases and text-mining

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FRAT1 — TCF7

Text-mined interactions from Literome

van Amerongen et al., Cell cycle (Georgetown, Tex.) 2005 : By binding to GSK3, Frat prevents the phosphorylation and concomitant degradation of beta-catenin and allows the activation of downstream target genes by beta-catenin/TCF complexes
Wang et al., Int J Cancer 2008 (Carcinoma, Squamous Cell...) : In addition, FRAT1 overexpression induced the nuclear accumulation of beta-catenin and promoted the transcriptional activity of beta-catenin/TCF ... In addition, FRAT1 overexpression induced the nuclear accumulation of beta-catenin and promoted the transcriptional activity of beta-catenin/TCF