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Towatari et al., Hematol J 2004
(MAP Kinase Signaling System) :
Involvement of mitogen activated protein kinase in the cytokine regulated phosphorylation of transcription factor GATA-1 ... Here we demonstrate a role for MAP kinase ( MAPK ) signalling in the control of GATA-1 phosphorylation ... We show that EGF induced MAPK signalling results in the phosphorylation of ectopically expressed GATA-1 in COS cells
Yu et al., J Biol Chem 2005
:
MAPK mediated phosphorylation of GATA-1 promotes Bcl-XL expression and cell survival ... Taken together, our data demonstrate that MAPK dependent GATA-1 phosphorylation is important for its transactivation of the E4bp4 gene, Bcl-X ( L ) expression and cell survival