Gene interactions and pathways from curated databases and text-mining

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GNRH1 — MMP16

Text-mined interactions from Literome

Goto et al., J Endocrinol 1999 : In this study we assessed the effect of GnRH on MMP expression and induction of structural involution of developed corpora lutea of superovulated rats using GnRHa
Cheung et al., Cancer Res 2006 (Neoplasm Invasiveness...) : Knockdown of the GnRH receptor using small interfering RNA significantly inhibited the GnRH induced MMP activation, invasion, and migration ... In addition, we showed that the c-Jun NH ( 2 ) -terminal kinase, but not extracellular signal regulated kinase 1/2 or p38 mitogen activated protein kinase, signaling pathway was critical for GnRH mediated up-regulation of MMP , cell invasion, and motility