Gene interactions and pathways from curated databases and text-mining

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GPR12 — PHKA2

Text-mined interactions from Literome

Felsch et al., Curr Biol 1999 (Sarcoma, Ewing) : G-protein coupled receptor signaling and other stimuli of Pyk2 kinase activity significantly block the interaction between EWS and Pyk2
Shi et al., J Biol Chem 2004 : Pyk2 is a member of the focal adhesion kinase family and can be activated by c-Src, epidermal growth factor receptor (EGFR), Janus kinase 1, tyrosine kinases, and G-protein coupled receptor signaling
Ohanian et al., Hypertension 2005 : Role of the actin cytoskeleton in G-protein coupled receptor activation of PYK2 and paxillin in vascular smooth muscle
Guo et al., Eur J Biochem 1998 : Further studies indicate that Pyk2 phosphorylation, but not MAPK activation, is dependent on a pertussis toxin-sensitive G-protein coupled receptor as well as partially on actin cytoskeleton