Gene interactions and pathways from curated databases and text-mining

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CXCL2 — GRAP2

Text-mined interactions from Literome

Petrai et al., Int J Biochem Cell Biol 2008 : In human microvascular endothelial cells, which selectively express CXCR3-B, in a cell cycle dependent fashion, CXCL10 and CXCL4 increased the enzymatic activity of p38 ( MAPK )
Chen et al., Molecular vision 2011 : Inhibition of p38MAPK , phosphoinositide 3-kinase (PI3K)-Akt and nuclear factor-kappaB ( NF-?B ), with the inhibitors SB203580, LY294002 and pyrrolydine dithiocarbamate ( PDTC ) respectively, reduced IL-17 ( 100 ng/ml ) mediated production of CXCL8 , CCL2, and IL-6 in a concentration dependent manner
Dumitru et al., J Leukoc Biol 2012 (Head and Neck Neoplasms...) : Most importantly, HNC induced p38-MAPK activation strongly stimulates the release of CCL4, CXCL8 , and MMP9 by neutrophils
Blume et al., Eur Respir J 2013 (Asthma...) : Inhibition of the extracellular signal regulated kinase 1/2 and p38 mitogen activated protein kinase pathways selectively blocked apical CXCL8/IL-8 release via a post-transcriptional mechanism