Liu et al., Cancer Res 2003
(Lung Neoplasms...) :
In this study, we test the possibility that HDAC inhibitor may increase RECK expression to inhibit MMP activation and cancer cell invasion
Kumamoto et al., Int J Cancer 2009
(Colonic Neoplasms...) :
MMP13 expression was further induced by coexpression of ING2 with HDAC1 or with mSin3A, suggesting that the ING2-HDAC1-mSin3A complex members regulates expression of MMP13 Wang et al., J Cereb Blood Flow Metab 2011
(Brain Edema...) :
Our findings suggest that BBB protection by VPA involves HDAC inhibition mediated suppression of NF-?B activation, MMP-9 induction, and tight junction degradation