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HDAC2 — STAT1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: STAT1 → HDAC2 (increases, HDAC2 Activity) Klampfer et al., J Biol Chem 2004*
  Evidence: silencing of HDAC1, HDAC2, and HDAC3 through RNA interference markedly decreased IFNgamma-driven gene activation and that overexpression of HDAC1, HDAC2, and HDAC3 enhanced STAT1-dependent transcriptional activity.

Text-mined interactions from Literome

Klampfer et al., J Biol Chem 2004 (Inflammation) : In this study we demonstrated that inhibitors of histone deacetylase (HDAC) activity, butyrate, trichostatin A, and suberoylanilide hydroxamic acid, prevented IFNgamma induced JAK1 activation, STAT1 phosphorylation, its nuclear translocation, and STAT1 dependent gene activation
Ivanov et al., Oncogene 2007 : Involvement of HDAC activity in STAT1 regulation was validated by TSA inhibition and chromatin immunoprecipitation ( ChIP ) assay