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CDK2 — HES1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of CCNE1-CDK2 → HES1 (decreases, CCNE1/CDK2 Activity) Hartman et al., Oncogene 2004*
  Evidence: Expression of HES-1 in T47D cells inhibited G(1)/S-phase transition and activation of Cdk2 elicited by estrogen.

Text-mined interactions from Literome

Hartman et al., Oncogene 2004 : Expression of HES-1 in T47D cells inhibited G1/S-phase transition and activation of Cdk2 elicited by estrogen
Katsuki et al., Biochem Biophys Res Commun 2008 : CCN3 transfection to Kusa-A1 inhibited osteogenic differentiation and cell proliferation, which is accompanied by upregulation of Hes/Hey , Notch downstream targets, and p21, a CDK inhibitor