Gene interactions and pathways from curated databases and text-mining

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HSF4 — MYB

Text-mined interactions from Literome

Tanikawa et al., J Biol Chem 2000 : p53 suppresses the c-Myb induced activation of heat shock transcription factor 3 ... This suggests that the c-Myb induced HSF3 activation may contribute to the growth regulated expression of HSPs ... Induction of p53 by a genotoxic reagent in DT40 cells disrupts the HSF3-c-Myb interaction and down-regulates the expression of certain HSPs. Mutated forms of p53 found in certain tumors did not inhibit c-Myb induced HSF3 activation ... The regulation of HSF3 activity by c-Myb and p53 sheds light on the molecular events that govern HSP expression during cellular proliferation and apoptosis
Tanikawa et al., Blood Cells Mol Dis 2001 : The c-Myb induced activation of HSF3 is negatively regulated by the p53 tumor suppressor protein
Kanei-Ishii et al., Science 1997 : Activation of heat shock transcription factor 3 by c-Myb in the absence of cellular stress