We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to MTOR


Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Gazitt et al., Int J Oncol 2009 (Bone Neoplasms...) : We used 17-AAG to inhibit Hsp90 and rapamycin to inhibit mTOR , in the osteosarcoma cell lines, HOS and KHOS/NP
Surova et al., Fiziolohichnyń≠ zhurnal (Kiev, Ukraine : 1994) 2009 : The changes of mRNA levels of genes of heat shock proteins HSP70 and HSP90 , antiapoptotic protein Bcl2 and key regulator of autophagy FRAP in cardiomyocytes culture were established
Shimamura et al., Cancer Res 2008 (Adenocarcinoma...) : In contrast, Hsp90 inhibition overcomes these limitations in vitro and depletes cells of EGFR, other RTKs, and phospho-Akt and inhibits mTOR signaling whether or not T790M is present
Delgoffe et al., Mol Immunol 2009 : Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation