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FAS — HSPG2

Text-mined interactions from Literome

Shin et al., Comp Biochem Physiol B Biochem Mol Biol 2000 : We have previously reported that Fas cross linking resulted in the activation of phosphatidylcholine-specific phospholipase C ( PC-PLC ) and the subsequent activation of protein kinase C ( PKC ) and phospholipase D ( PLD ) in A20 cells ... In an attempt to correlate the existence of PC-PLC activity and activation of PLD by Fas activation among various Fas expressing murine cell lines, we have investigated the effect of anti-Fas monoclonal antibody on PC-PLC and PLD activities in A20, P388D1 and YAC-1 cell lines
Kim et al., Exp Mol Med 2001 (Lymphoma) : There were no effects of genistein on Fas induced activation of PC-PLC and protein kinase C
Cifone et al., EMBO J 1995 (Lymphoma) : Activation of a phosphatidylcholine-specific phospholipase C ( PC-PLC ) was also detected which appeared to be a requirement for subsequent acidic sphingomyelinase (aSMase) activation, since PC-PLC inhibitor D609 blocked Fas/APO-1 induced aSMase activation, but not Fas/APO-1 induced neutral sphingomyelinase (nSMase) activation