Gene interactions and pathways from curated databases and text-mining

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CAPN6 — IFI27

Text-mined interactions from Literome

Patel et al., J Biol Chem 2000 : Inhibition of calpain by either ALLN or by overexpression of calpastatin blocks the degradation of p27
Akashiba et al., J Neurochem 2006 : In this study, we demonstrate that reductions of both p27 and neuronal viability were dependent on activity of calpain , a Ca ( 2+ ) -dependent protease, but not on activity of caspase 3 ... It reduced p27 expression level in the nucleus in a calpain dependent manner
Akashiba et al., J Biol Chem 2008 (Calcium Signaling...) : Both striatal p27 down-regulation and cell death provoked by 3-NP were dependent on calpain activity
Kashiwagi et al., Calcif Tissue Int 2011 : Collectively, calpain regulates cell proliferative function by modulating both transcription and degradation of p27 ( Kip1 ) in osteoblasts