Gene interactions and pathways from curated databases and text-mining

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FOXO1 — IGF1R

Text-mined interactions from Literome

Liu et al., J Endocrinol 2007 : FOXO1 is a member of the forkhead transcriptional factor family, but how insulin and IGF-I receptor signaling regulate FOXO1 in cardiomyocytes is not well understood ... In cardiomyocytes, activation of IGF-I receptor and insulin receptor lead to rapid phosphorylation of FOXO1
Cao et al., Cancer Res 2010 (Rhabdomyosarcoma, Alveolar...) : We also provide the first direct evidence that FGFR4 and IGF1R are the targets for PAX3-FKHR