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IGF2 — MMP14

Text-mined interactions from Literome

Zhang et al., Oncogene 2003 (Carcinoma, Lewis Lung...) : Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling ... Here, we investigated the role of IGF-IR in the regulation of MT1-MMP
Stawowy et al., Biochem Biophys Res Commun 2004 : Both, IGF-1 and PDGF-BB, induced MT1-MMP expression, but only IGF-1 mediated MT1-MMP induction was inhibited by dec-CMK
Hiden et al., J Clin Endocrinol Metab 2012 (Diabetes, Gestational...) : Fetal insulin and IGF-II contribute to gestational diabetes mellitus ( GDM ) -associated up-regulation of membrane-type matrix metalloproteinase 1 ( MT1-MMP ) in the human feto-placental endothelium ... Pathophysiological levels of insulin and IGF-II , but not IGF-I and glucose, stimulated MT1-MMP expression in fpEC by phosphatidylinositol 3-kinase signals relayed through the insulin, but not IGF-I, receptor