Gene interactions and pathways from curated databases and text-mining

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IGF2 — TCF3

Text-mined interactions from Literome

Palamarchuk et al., FEBS Lett 1999 : In the present study, we demonstrate that a liver enriched transcription factor , hepatocyte nuclear factor 3beta ( HNF-3beta ), is an activator of the chum salmon IGF-II gene
Morali et al., Oncogene 2001 : We can show that ( 1 ) IGF-II induces a rapid epithelium to mesenchymal transition ; ( 2 ) IGF1R, the receptor for IGF-II, belongs to the same membrane complex as E-cadherin and beta-catenin ; ( 3 ) IGF-II induces a redistribution of beta-catenin from the plasma membrane to the nucleus and an intracellular sequestration and degradation of E-cadherin ; ( 4 ) IGF-II induces the transcription of beta-catenin/TCF-3 target genes
Markljung et al., PLoS Biol 2009 (Genetic Diseases, Inborn) : ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth
Borensztein et al., Development 2013 : In addition, Igf2 also negatively regulates Myod expression, possibly by reducing the expression of the Srf transcription factor , a known Myod activator
Zvibel et al., J Cell Physiol 1995 (Carcinoma, Hepatocellular...) : The transcription factor HNF-3 beta mRNA and protein levels of the bile duct markers, CK19 and GGT, were also increased in the presence of IGF II
Castillo et al., Endocrinology 1997 : As analyzed by Western blot, IGF-1 did not alter GHF-1/Pit-1 protein levels in GH4C1 cells but reduced the levels of the transcription factor in GH3 cells