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IKBKB — MMP9

Text-mined interactions from Literome

Rhee et al., Mol Immunol 2007 : BMS-345541, an IKK-2 inhibitor also inhibited the expression of MMP-9 gene induced by CpG-ODN
Fukuyama et al., Mol Carcinog 2007 (Colorectal Neoplasms) : Role of IKK and oscillatory NFkappaB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells
Kim et al., Mol Cancer Res 2008 (Glioma) : Here, we report that the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin ( 17-AAG ) blocks MMP-9 secretion and that HA-induced nuclear factor-kappaB (NF-kappaB) activation is mediated by IkappaB kinase , which phosphorylates the NF-kappaB inhibitor IkappaBalpha and promotes its degradation
Liu et al., Chinese journal of cancer 2010 (Neoplasm Invasiveness...) : Moreover, the inhibition of IKKbeta inhibited the expressions of MMP-2 and MMP-9 ... IKKbeta may play a crucial role in the OPN induced activation of MMP-2 and MMP-9 via NF-kappaB mediated IkappaB/IKKbeta pathways
Lee et al., Toxicol Lett 2010 (Carcinoma, Hepatocellular...) : First, we suggest that the expression of MMP-9 by TPA involves phosphorylation of IKK , p38, and PKC in hepG2
Liu et al., Cancer Lett 2010 (Prostatic Neoplasms) : Moreover, the inhibition of IKK-2 can suppress MMP-2 and MMP-9 expressions, in contrast, the inhibition of IKK-1 has no effects on the OPN, MMP-2 and MMP-9 expression levels ... Thus, this study demonstrated that OPN knockdown could downregulate MMP-2 and MMP-9 expressions result in inhibiting the malignant physiological behaviors of PC-3 cell and that IKK-2 may play a crucial role in OPN induced MMP-2 and MMP-9 expressions via NF-kappaB mediated signaling pathways