Gene interactions and pathways from curated databases and text-mining

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IKBKB — TCF25

Text-mined interactions from Literome

Gasparian et al., J Cell Sci 2002 (Carcinoma...) : The role of IKK in constitutive activation of NF-kappaB transcription factor in prostate carcinoma cells
Chen et al., Cancer Res 2004 (Carcinoma, Squamous Cell...) : We additionally characterized the role of IKKbeta , a regulator of the nuclear factor-kappaB transcription factor , during hypoxia
Sumi et al., Yakugaku Zasshi 2007 : Although IKKbeta activates transcription factor NF-kappaB and PTP1B negatively regulates the receptor-protein tyrosine kinase, such as epidermal growth factor receptor (EGFR) in cells, covalent modification of these proteins caused by 1,2-NQ results in inhibition of NF-kappaB activity and transactivation of EGFR
Bockhart et al., J Neurosci 2009 (Ion Channel Gating) : Inhibitor kappaB kinase (IKK) regulates the activity of the transcription factor nuclear factor-kappa B that normally protects neurons against excitotoxicity
Scotto d'Abusco et al., Arthritis Res Ther 2010 : Inhibitor kappaB kinase (IKK)alpha and IKKbeta are kinases involved in the activation of the NF-kappaB transcription factor
Nagarajan et al., BMC bioinformatics 2010 : Nuclear factor kappa B ( NF-?B ) is a chief nuclear transcription factor that controls the transcription of various genes ; and its activation is tightly controlled by Inhibitor kappa B kinase (IKK)