Gene interactions and pathways from curated databases and text-mining

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FOS — IKBKG

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Chang et al., Exp Cell Res 2002 : This suggests that IL-8 induction by LTbetaR is via TRAFs elicited signaling pathways, including NIK/IKK dependent NF-kappaB activation and ASK/MKK/JNK dependent AP-1 activation
Auwerx et al., Oncogene 1992 (Cell Transformation, Neoplastic) : AP-1 ( Fos-Jun ) regulation by IP-1 : effect of signal transduction pathways and cell growth
Auwerx et al., Cell 1991 : IP-1 specifically blocks DNA binding of AP-1 from nuclear extracts and of in vitro synthesized Fos/Jun proteins
Chang et al., Nat Med 2009 (Osteoporosis) : Inhibition of IKK-NF-kappaB enhances the expression of Fos related antigen-1 (Fra-1) , an essential transcription factor involved in bone matrix formation in vitro and in vivo